PATHiVAR estimates the functional impact that mutations have over the human signalling network.
PATHiVAR analyses VCF files, extract the deleterious mutations, locate them over the signalling
pathways in the selected tissue (with the appropriate expression pattern) and provides a
comprehensive, graphic and interactive view of the predicted signal transduction probabilities
across the different signalling pathways.
PATHiVAR web application makes an intensive use of the HTML5 standard and other cutting-edge web
technologies such as
Web Components, so only modern web browsers are fully supported, these include Chrome 36+, Firefox 32+, IE
10+, Safari 7+
and Opera 24+.